Efficient filtering of adult content using textual information

Nowadays adult content represents a non negligible proportion of the Web content. It is of the utmost importance to protect children from this content. Search engines, as an entry point for Web navigation are ideally placed to deal with this issue. In this paper, we propose a method that builds a safe index i.e. adult-content free for search engines. This method is based on a filter that uses only textual information from the web page and the associated URL

Distribution, Approximation and Probabilistic Model Checking

AbstractAPMC is a model checker dedicated to the quantitative verification of fully probabilistic systems against LTL formulas. Using a Monte-Carlo method in order to efficiently approximate the verification of probabilistic specifications, it could be used naturally in a distributed framework. We present here the tool and its distribution scheme, together with extensive performance evaluation, showing the scalability of the method, even on clusters containing 500+ heterogeneous workstations

Rocovo : Robust Communal Publication Scheme

International audienceWe study the problem of designing a robust validation method for publishing content on social websites. In such websites, users can propose their content to the community. Since the data is user generated, a huge volume of content is pub-lished every day on a successful platform. An important problem arising in such websites is that users have to filter all the published content to find something interesting. This filtering can be assisted by the website, thanks to a recom-mendation mechanism. An even more important problem is that the context is adversarial: some malicious users try to trick the system in order to either publish their own content or make sure that specific content is not published. There-fore, users might not find the content they are interested in either because it is diluted in an ocean of spam or because it was maliciously blocked from publication. In this paper, we present Rocovo (RObust COmmunal VOting), a two phases mechanism that allows for the automatic management of the publication process in a robust and communal manner

Efficient filtering of adult content using textual information

International audienceNowadays adult content represents a non negligible proportion of the Web content. It is of the utmost importance to protect children from this content. Search engines, as an entry point for Web navigation are ideally placed to deal with this issue. In this paper, we propose a method that builds a safe index i.e. adult-content free for search engines. This method is based on a filter that uses only textual information from the web page and the associated URL

Texturing optimization for bifacial n-PERT: are pyramids and/or black silicon the way to go for thinner devices?

International audienc

Texturing optimization for bifacial n-PERT: are pyramids and/or black silicon the way to go for thinner devices?

International audienc

Fecal incontinence in patients with spina bifida The target is the rectum

International audienceAims - The prevalence rate of severe fecal incontinence (FI) in adults with spina bifida (SB) is high. The physiological basis of FI in SB has not been clearly established, which contributes to inadequate care. The aim was to better characterize a large cohort of adults with special consideration of anorectal physiology.Methods - A multidisciplinary team from a French referral centre for SB prospectively collected data on patients who had an anorectal manometry. Factors associated with severe FI (Cleveland clinical incontinence score ≥ 9) were assessed in a multivariate analysis model.Results - A total of 132 adults with SB (sex ratio M/F: 55 [41.7%]/77 [58.3%]; mean age of 38.2 [11.6] years old) were assessed. Among these patients, 83/132 (62.9%) suffered from severe FI. Rectal perception was not evaluable among 17 patients who had a latex allergy. Overall, 29/115 (25.2%) had maximal tolerable volume (MTV) > 330 mL or no sensation. The absence of anal canal sensitivity, MVT > 330 mL and the amplitude of the recto-anal inhibitory reflex (RAIR) >75% after a rectal isovolumic inflation of 50 mL were significantly associated with severe FI in the multivariate analysis model. Neither neurological level nor other neurological features were associated with severe FI.Conclusions - This study showed that FI in patients with SB is mainly associated with rectal abnormalities. This should be taken into consideration to improve incontinence management of patients with SB.<br

Defecation disorders in Spina Bifida Realistic goals and best therapeutic approaches

International audienceAims - Spina Bifida (SB) is a rare congenital condition that frequently impairs the neurological control of both fecal continence and defecation. Several therapeutic strategies have been proposed but impact assessment is lacking. Our objectives were to quantify the symptomatic improvement and to determine the optimal strategy in this rare condition where randomized controlled trials are difficult to conduct. Methods - Data were extracted from a prospective database. The present analysis focused on patients having undergone at least two gastroenterological assessments. A standardized therapeutic approach was used from the first visit. Improvement was quantified by the variation of quantified symptomatic scores. Results - The data of of 57 adults with SB (gender F/M: 30/27 [52.6/47.4%]; mean age: 33.8 [18.5] years) were extracted. After a mean follow-up of 46 months, 23/57 patients (40.4%) had at least improvement of one point of the Cleveland Clinic Incontinence score (CCIS); 13/57 (22.8%) reported a significant improvement of continence (delta score >50%). Five of the twelve patients (41.6%) with CCIS < 5 at baseline became incontinent over time. The neurological level was not associated with a worse continence outcome. Work on stool consistency and transanal irrigation were the most useful strategies in those with significant improvement of continence. Conclusions - Using conventional strategies, a benefit on fecal continence occurs in only one out of five patients suffering from Spina Bifida and continent patients at baseline can develop fecal incontinence over time. A strategy targeting improved control of defecation (transanal irrigation) and a standardization of follow-up protocol might be beneficial

Altered epithelial barrier functions in the colon of patients with spina bifida

International audienceOur objectives were to better characterize the colorectal function of patients with Spina Bifida (SB). Patients with SB and healthy volunteers (HVs) completed prospectively a standardized questionnaire, clinical evaluation, rectal barostat, colonoscopy with biopsies and faecal collection. The data from 36 adults with SB (age: 38.8 [34.1-47.2]) were compared with those of 16 HVs (age: 39.0 [31.0-46.5]). Compared to HVs, rectal compliance was lower in patients with SB (p = 0.01), whereas rectal tone was higher (p = 0.0015). Ex vivo paracellular permeability was increased in patients with SB (p = 0.0008) and inversely correlated with rectal compliance (r = − 0.563, p = 0.002). The expression of key tight junction proteins and inflammatory markers was comparable between SB and HVs, except for an increase in Claudin-1 immunoreactivity (p = 0.04) in SB compared to HVs. TGFβ1 and GDNF mRNAs were expressed at higher levels in patients with SB (p = 0.02 and p = 0.008). The levels of acetate, propionate and butyrate in faecal samples were reduced (p = 0.04, p = 0.01, and p = 0.02, respectively). Our findings provide evidence that anorectal and epithelial functions are altered in patients with SB. The alterations in these key functions might represent new therapeutic targets, in particular using microbiota-derived approaches. Clinical Trials: NCT02440984 and NCT03054415

Contrast-enhanced CT texture parameters as predictive markers of high-risk urodynamic features in adult patients with spina bifida

International audienceOBJECTIVE : To investigate computed tomography (CT) texture analysis of the bladder wall as a predictor of urodynamics findings in adult patient with spina bifida.METHODS : A single-center prospective trial was conducted from March 2015 to March 2017 including all consecutive adult spina bifida patients seen for urodynamic testing. A contrast-enhanced abdominal CT was systematically performed in all patients during the same visit. Texture features of the bladder wall related to the gray-level histogram and gray-level co-occurrence were evaluated on CT images. Multivariate analysis was performed to identify independent predictors of poor bladder compliance and detrusor overactivity among clinical and texture parameters.RESULTS : Fourty patients were included. The Lasso penalized logistic regression analysis identified 2 texture parameters as potential predictors of poor bladder compliance: Skewness (coefficient weight, -1.81) and S.1.1.SumVarnc (coefficient weight, -3.52). Multivariate logistic regression analysis confirmed skewness (odds ratio [confidence interval 95%] = 0.40 [0.14, 0.97], P = .04) as an independent predictor of poor bladder compliance. The Lasso penalized logistic regression analysis identified one texture parameters as potential predictor of detrusor overactivity: Kurtosis (coefficient weight, -3.52), which was confirmed in multivariate logistic regression analysis (odds ratio [confidence interval 95%] = 1.12 [1.01, 1.55], P = .02).CONCLUSION : Our findings demonstrate that CT texture analysis of the bladder wall might be an interesting tool to identify spina bifida patients with high risk urodynamic features